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Associated factors with Premenstrual syndrome and Premenstrual dysphoric disorder among female medical students: A cross-sectional study

Ngo Dinh Trieu Vy, Linh Phuong Bui, Long Bao Hoang, My Thi Tra Tran, Vũ Quốc Huy Nguyễn, Mạnh Linh Trần, Tung T. Pham

2023PLoS ONE18 citationsDOIOpen Access PDF

Abstract

AIM: The study aimed to determine potential risk factors associated with Premenstrual Syndrome and Premenstrual Dysphoric Disorder. METHODS: Three hundred two female student participants who were 18-45 years old completed a questionnaire including demographic characteristics, lifestyle factors, and a Vietnamese Premenstrual Syndrome Screening Tool. We then followed up participants during at least two menstrual cycles using the Daily Record of Severity of Problems. The Premenstrual Syndrome and Premenstrual Dysphoric Disorder diagnosis was established using The Carolina Premenstrual Assessment Scoring System, based on the American College of Obstetrics and Gynecology and Diagnostic and Statistical Manual of Mental Disorders. RESULTS: According to the Carolina Premenstrual Assessment Scoring System, 35 out of 302 students (11.6%; 95%CI: 8.2-15.7%) met the diagnosis of PMS (31 students) or PMDD (4 students). We found that age at menarche (PR = 0.77, 95%CI: 0.63-0.96), having negative Rh blood type (PR = 4.43, 95%CI: 1.95 to 10.08), being moderately depressed or higher (PR = 2.81, 95%CI: 1.24 to 6.36), and consuming caffeine more than three times per week were statistically associated with having Premenstrual Syndrome or Premenstrual Dysphoric Disorder after adjusting for other variables. CONCLUSION: The prominent risk factors for Premenstrual Syndrome and Premenstrual Dysphoric Disorder were negative Rhesus blood type, menarche age, caffeine consumption, and self-reported depression.

Topics & Concepts

Premenstrual dysphoric disorderMenarcheMedicineCross-sectional studyPremenstrual TensionDepression (economics)MenstruationMenstrual cyclePsychiatryGynecologyObstetricsInternal medicineHormoneMacroeconomicsEconomicsPathologyMenstrual Health and DisordersPerfectionism, Procrastination, Anxiety StudiesReproductive Health and Contraception