Biosynthesis of α-bisabolene from low-cost renewable feedstocks by peroxisome engineering and systems metabolic engineering of the yeast <i>Yarrowia lipolytica</i>
Baixiang Zhao, Yahui Zhang, Yaping Wang, Zhihui Lu, Lin Miao, Shuhui Wang, Zhuo Li, Xu Sun, Yuqing Han, Sicheng He, Ziyuan Zhang, Dongguang Xiao, Cuiying Zhang, Jee Loon Foo, Adison Wong, Aiqun Yu
Abstract
Establishing efficient synthetic pathways for microbial production of biochemicals is often hampered by competing pathways and insufficient precursor supply.
Topics & Concepts
YarrowiaMetabolic engineeringYeastSynthetic biologyChemistryBiosynthesisPeroxisomeMetabolic pathwayBiochemistryRenewable energyBiochemical engineeringMetabolismBiologyEnzymeComputational biologyEngineeringGeneEcologyMicrobial Metabolic Engineering and BioproductionPlant biochemistry and biosynthesisEnzyme Catalysis and Immobilization