Litcius/Paper detail

How I treat myeloproliferative neoplasms in pregnancy

Susan Robinson, Monica Ragheb, Claire Harrison

2023Blood19 citationsDOIOpen Access PDF

Abstract

ABSTRACT: Although myeloproliferative neoplasms (MPNs) are traditionally considered diseases of adults in their sixth or seventh decade, these conditions do occur in young patients; for example, for essential thrombocythemia, in particular, there is a second peak in women of reproductive age. Therefore, pregnancy is an uncommon but not rare occurrence and clinical challenge in some scenarios. Here, we discuss in detail our local approach to the management of pregnancy in patients with MPN while taking a case-based approach. We include relevant updates in the field and point to a future research strategy that should be internationally focused to obtain as much information in as short a time as possible.

Topics & Concepts

Essential thrombocythemiaPregnancyMedicineMyeloproliferative DisordersPediatricsPolycythemia veraIntensive care medicineObstetricsInternal medicineBiologyGeneticsMyeloproliferative Neoplasms: Diagnosis and TreatmentKruppel-like factors researchAcute Myeloid Leukemia Research