Litcius/Paper detail

Research progress in gene editing technology

Sheng Huang, Yali Yan, Fei Su, Xiaorui Huang, Dandan Xia, Xinxin Jiang, Yinghui Dong, Ping Lv, Fangyuan Chen, Yanwei Lv

2021Frontiers in Bioscience-Landmark31 citationsDOIOpen Access PDF

Abstract

As a tool for modifying the genome, gene editing technology has developed rapidly in recent years, especially in the past two years. With the emergence of new gene editing technologies, such as transposon editing tools, numerous advancements have been made including precise editing of the genome, double base editing, and pilot editing. This report focuses on the development of gene editing tools in recent years, elaborates the progress made in classic editing tools, base editor and other new editing tools, and provides insights into challenges and opportunities.

Topics & Concepts

Genome editingComputer scienceRNA editingComputational biologyGenomeGeneBiologyGeneticsGene expressionCRISPR and Genetic EngineeringViral gastroenteritis research and epidemiologyVirus-based gene therapy research