<i>cis</i>-9-Hexadecenal, a Natural Compound Targeting Cell Wall Organization, Critical Growth Factor, and Virulence of <i>Aspergillus fumigatus</i>
Shanu Hoda, Lovely Gupta, Jata Shankar, Alok Gupta, Pooja Vijayaraghavan
Abstract
-9-hexadecenal and PKS at Thr-264 and Ser-171 residue via hydrogen bonding at a low binding energy of -4.95 kcal/mol.
Topics & Concepts
Aspergillus fumigatusVirulenceMelaninHomology modelingDocking (animal)MicrobiologyVirulence factorBiologyBroth microdilutionChemistryBiochemistryStereochemistryGeneIn vitroEnzymeMinimum inhibitory concentrationMedicineNursingAntifungal resistance and susceptibilityMicrobial Natural Products and BiosynthesisPlant Pathogens and Fungal Diseases