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First Autochthonous West Nile Lineage 2 and Usutu Virus Infections in Humans, July to October 2018, Czech Republic

Hana Zelená, Jana Kleinerová, Silvie Šikutová, Petra Straková, Hana Kocourková, Roman Stebel, Petr Husa, Petr Husa, Eva Tesařová, Hana Lejdarová, Oldřich Šebesta, Peter Juráš, Renata Ciupek, Jakub Mrázek, Ivo Rudolf

2021Pathogens22 citationsDOIOpen Access PDF

Abstract

We present epidemiological, clinical and laboratory findings of five Czech patients diagnosed with autochthonous mosquito-borne disease-four patients with confirmed West Nile virus (WNV) and one patient with Usutu virus (USUV) infections, from July to October 2018, including one fatal case due to WNV. This is the first documented human outbreak caused by WNV lineage 2 in the Czech Republic and the first record of a neuroinvasive human disease caused by USUV, which illustrates the simultaneous circulation of WNV and USUV in the country.

Topics & Concepts

OutbreakWest Nile virusCzechVirologyLineage (genetic)EpidemiologyDiseaseArbovirusHuman diseaseBiologyVirusGeographyMedicinePathologyPhilosophyBiochemistryGeneLinguisticsMosquito-borne diseases and controlViral Infections and VectorsMalaria Research and Control