Urinary glycoproteins associated with aggressive prostate cancer
Mingming Dong, T. Mamie Lih, Shao‐Yung Chen, Kyung-Cho Cho, Rodrigo Vargas Eguez, Naseruddin Höti, Yangying Zhou, Weiming Yang, Leslie A. Mangold, Daniel W. Chan, Zhen Zhang, Lori J. Sokoll, Alan W. Partin, Hui Zhang
Abstract
We have identified glycopeptides of urinary glycoproteins associated with aggressive prostate cancer using a quantitative mass spectrometry-based glycoproteomic approach and demonstrated their potential to serve as noninvasive urinary glycoprotein biomarkers worthy of further validation by a multi-center study.
Topics & Concepts
Prostate cancerMedicineProstateUrinary systemOncologyConfidence intervalInternal medicineCohortCancerUrologyAdvanced Proteomics Techniques and ApplicationsCancer, Lipids, and MetabolismMolecular Biology Techniques and Applications