Activation of NF-κB by TOPK upregulates Snail/Slug expression in TGF-β1 signaling to induce epithelial-mesenchymal transition and invasion of breast cancer cells
Young-Ju Lee, Jung‐Hwan Park, Sang‐Muk Oh
Topics & Concepts
SlugGene knockdownEpithelial–mesenchymal transitionSnailCancer researchBreast cancerTransforming growth factorCancer cellNF-κBSignal transductionCancerMetastasisBiologyMedicineInternal medicineCell cultureCell biologyEcologyGeneticsFOXO transcription factor regulationMechanisms of cancer metastasisMetabolism, Diabetes, and Cancer