Acute cardiometabolic effects of brief active breaks in sitting for patients with rheumatoid arthritis
Ana Jéssica Pinto, Kamila Meireles, Tiago Peçanha, Bruna Caruso Mazzolani, Fabiana Infante Smaira, Diego Augusto Nunes Rezende, Fabiana Braga Benatti, Ana Cristina de Medeiros Ribeiro, A.L.S. Pinto, Fernanda Rodrigues Lima, Samuel Katsuyuki Shinjo, Wagner S. Dantas, Natalie A. Mellett, Peter J. Meikle, Neville Owen, David W. Dunstan, Hamilton Roschel, Bruno Gualano
Abstract
Exercise is a treatment in rheumatoid arthritis but is challenging for some patients. Light-intensity breaks in sitting could be a promising alternative. Our findings show beneficial, but differential, cardiometabolic effects of active breaks in sitting and exercise in patients with rheumatoid arthritis. Breaks in sitting mainly improved glycemic and inflammatory markers, whereas exercise improved lipidomic and hypotensive responses. Breaks in sitting show promise in offsetting aspects of cardiometabolic disturbance associated with prolonged sitting in rheumatoid arthritis.