Inhibition of LRRK2 restores parkin-mediated mitophagy and attenuates intervertebral disc degeneration
Jialiang Lin, Xuan-Qi Zheng, Zengjie Zhang, Jinru Zhuge, Zhenxuan Shao, Chongan Huang, Jie Jin, Ximiao Chen, Yu Chen, Yaosen Wu, Naifeng Tian, Liaojun Sun, Weiyang Gao, Yifei Zhou, Xiangyang Wang, Xiaolei Zhang
Topics & Concepts
ParkinMitophagyDegeneration (medical)Intervertebral discLRRK2MedicineChemistryAnatomyPathologyAutophagyParkinson's diseaseBiochemistryApoptosisDiseaseSpine and Intervertebral Disc PathologyParkinson's Disease Mechanisms and TreatmentsSpondyloarthritis Studies and Treatments