Zirconium oxide nano-catalyzed synthesis of pharmacologically important bis(indolyl)methanes: a highly efficient and mild approach
Komal Rathi, Om Shanker Tiwari, Varun Rawat, Jawahar L. Jat, Dinesh Kumar Yadav, Ved Prakash Verma
Abstract
a co-precipitation method demonstrates exceptional efficacy, leading to favourable yields of the target bis(indolyl)methanes 3a-z. The versatility of this methodology is highlighted through substrate screening, showcasing its applicability to various aromatic aldehydes.
Topics & Concepts
CatalysisZirconiumNano-Zirconium oxideOxideChemistryCombinatorial chemistryOrganic chemistryNanotechnologyMaterials scienceComposite materialSynthesis of Indole DerivativesChemical Synthesis and ReactionsBioactive natural compounds