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Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial

Stephen A. Boorjian, Mehrdad Alemozaffar, Badrinath R. Konety, Neal D. Shore, Leonard G. Gomella, Ashish M. Kamat, Trinity J. Bivalacqua, Jeffrey S. Montgomery, Seth P. Lerner, Joseph E. Busby, Michael Poch, Paul L. Crispen, Gary D. Steinberg, Anne Schuckman, Tracy M. Downs, Robert S. Svatek, Joseph Mashni, Brian R. Lane, Thomas J. Guzzo, Gennady Bratslavsky, Lawrence I. Karsh, Michael Woods, Gordon Brown, Daniel Canter, Adam Luchey, Yair Lotan, Tracey L. Krupski, Brant A. Inman, Michael B. Williams, Michael S. Cookson, Kirk A. Keegan, Gerald L. Andriole, Alexander I. Sankin, Alan Boyd, Michael A. O’Donnell, David G. Sawutz, Richard Philipson, Ruth Coll, Vikram M. Narayan, F. Peter Treasure, Seppo Ylä‐Herttuala, Nigel Parker, Colin P. Dinney

2020The Lancet Oncology443 citationsDOIOpen Access PDF

Topics & Concepts

MedicineBladder cancerUrologyLymphovascular invasionPopulationInternal medicineCystectomyCarcinoma in situCancerOncologyClinical endpointClinical trialMetastasisEnvironmental healthBladder and Urothelial Cancer TreatmentsImmune responses and vaccinationsinterferon and immune responses
Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial | Litcius