Combined inhibition of EZH2 and the autotaxin-LPA-LPA2 axis exerts synergistic antitumor effects on colon cancer cells
Yang Long, Yuqin Wang, Mengxia Qu, Di Zhang, Xiaotian Zhang, Junjie Zhang, Junjie Zhang
Topics & Concepts
AutotaxinLysophosphatidic acidCancer researchColorectal cancerCancer cellEZH2CarcinogenesisCancerReceptorBiologyCell growthChemistryBiochemistryGene expressionGeneGeneticsSphingolipid Metabolism and SignalingEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy