High-frequency blood flow-restricted resistance exercise results in acute and prolonged cellular stress more pronounced in type I than in type II fibers
Thomas Bjørnsen, Mathias Wernbom, Gøran Paulsen, James F. Markworth, Sveinung Berntsen, Randall F. D’Souza, David Cameron‐Smith, Truls Raastad
Abstract
BFRRE has been reported to preferentially stress type I muscle fibers, as evidenced by HSP responses. We extend these findings by showing that the HSP responses occur in both fiber types but more so in type I fibers and that they can still be induced after a short-term training period. Furthermore, the reductions in glycogen content of type I fibers after strenuous frequent BFRRE in unaccustomed subjects can be prolonged (≥5 days), probably due to microdamage.
Topics & Concepts
Internal medicineImmunostainingGlycogenEndocrinologyHsp70MedicineShock (circulatory)Heat shock proteinBiologyImmunohistochemistryBiochemistryGeneExercise and Physiological ResponsesSports Performance and TrainingThermoregulation and physiological responses