Development of besifloxacin HCl loaded nanofibrous ocular inserts for the treatment of bacterial keratitis: In vitro, ex vivo and in vivo evaluation
Heybet Kerem Polat, Sibel Bozdağ Pehlivan, Ceren Özkul, Semih Çalamak, Naile Öztürk, Eren Aytekin, Ayşegül Fırat, Kezban Ulubayram, Sibel Kocabeyoğlu, Murat İrkeç, Sema Çalış
Topics & Concepts
Ex vivoIn vivoDrug deliveryPolyethylene glycolPEG ratioChemistryInsert (composites)CorneaIn vitroMaterials sciencePharmacologyBiomedical engineeringNanotechnologyMedicineOphthalmologyBiochemistryBiologyBiotechnologyEconomicsComposite materialFinanceAdvanced Drug Delivery SystemsDrug Solubulity and Delivery SystemsAntibiotics Pharmacokinetics and Efficacy