Unlocking full and fast conversion in photocatalytic carbon dioxide reduction for applications in radio-carbonylation
Serena Monticelli, Alex Talbot, Philipp Gotico, Fabien Caillé, Olivier Loreau, Antonio Del Vecchio, Augustin Malandain, Antoine Sallustrau, Winfried Leibl, Ally Aukauloo, Frédéric Taran, Zakaria Halime, Davide Audisio
Abstract
Abstract Harvesting sunlight to drive carbon dioxide (CO 2 ) valorisation represents an ideal concept to support a sustainable and carbon-neutral economy. While the photochemical reduction of CO 2 to carbon monoxide (CO) has emerged as a hot research topic, the full CO 2 -to-CO conversion remains an often-overlooked criterion that prevents a productive and direct valorisation of CO into high-value-added chemicals. Herein, we report a photocatalytic process that unlocks full and fast CO 2 -to-CO conversion (<10 min) and its straightforward valorisation into human health related field of radiochemistry with carbon isotopes. Guided by reaction-model-based kinetic simulations to rationalize reaction optimisations, this manifold opens new opportunities for the direct access to 11 C- and 14 C-labeled pharmaceuticals from their primary isotopic sources [ 11 C]CO 2 and [ 14 C]CO 2 .