An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing
Amanda L. Waterbury, Hui Si Kwok, Ceejay Lee, Domenic N. Narducci, Allyson M. Freedy, Cindy Su, Shaunak Raval, Andrew H. Reiter, William Hawkins, Kwangwoon Lee, Jiaming Li, Samuel M. Hoenig, Michael Vinyard, Philip A. Cole, Anders S. Hansen, Steven A. Carr, Malvina Papanastasiou, Brian B. Liau
Topics & Concepts
CorepressorPsychological repressionBiologyCrosstalkTranscription factorIntrinsically disordered proteinsCell biologyGene silencingEnhancerRepressorBasic helix-loop-helixMYBRegulation of gene expressionComputational biologyDNA-binding proteinGeneGeneticsBiophysicsPhysicsGene expressionOpticsGenomics and Chromatin DynamicsEpigenetics and DNA MethylationRNA Research and Splicing