<i>In Vitro</i> Synergistic Effects of Omadacycline with Other Antimicrobial Agents against Mycobacterium abscessus
Keiji Fujiwara, Akio Aono, Takahiro Asami, Kozo Morimoto, Keisuke Kamada, Yuta Morishige, Yuriko Igarashi, Kinuyo Chikamatsu, Yoshiro Murase, Hiroyuki Yamada, Akiko Takaki, Satoshi Mitarai
Abstract
0.009) showed significantly higher synergy against strains with rough morphotypes than those with smooth morphotypes. In conclusion, the checkerboard analyses revealed that the synergistic effects of OMC were observed most frequently with RFB, followed by CLR, TZD, CLO, IPM, and AMK. Furthermore, OMC tended to be more effective against rough-morphotype Mab strains.
Topics & Concepts
Mycobacterium abscessusAntimicrobialIn vitroMicrobiologyMycobacteriumAntibacterial agentChemistryBiologyAntibioticsBacteriaBiochemistryGeneticsMycobacterium research and diagnosisInfectious Diseases and MycologyTuberculosis Research and Epidemiology