Cinnamic acid derivatives: inhibitory activity against<i>Escherichia coli β</i>-glucuronidase and structure–activity relationships
Xing‐Nuo Li, Lu‐Xia Hua, Tao‐Shun Zhou, Ke-Bo Wang, Yuanyuan Wu, Mahmoud Emam, Xiaoze Bao, Jun Chen, Bin Wei
Abstract
in cinnamic acid derivatives was essential for EcGUS inhibition. These data are useful to design more potent cinnamic acid-type inhibitors of EcGUS.
Topics & Concepts
Escherichia coliCinnamic acidChemistryInhibitory postsynaptic potentialGlucuronidaseBiochemistryStructure–activity relationshipStereochemistryEnzymeBiologyIn vitroGeneNeuroscienceCancer therapeutics and mechanismsBioactive Compounds and Antitumor AgentsPhenothiazines and Benzothiazines Synthesis and Activities