Post-translational modifications comparative identification and kinetic study of infliximab innovator and biosimilars in serum using capillary electrophoresis-tandem mass spectrometry
Tessa Reinert, Pascal Houzé, Nathalie Mignet, Yannis‐Nicolas François, Rabah Gahoual
Topics & Concepts
ChemistryDeamidationBiosimilarInnovatorCapillary electrophoresisInfliximabMonoclonal antibodyPharmacologyTandem mass spectrometryIn vivoChromatographyContext (archaeology)Mass spectrometryLiquid chromatography–mass spectrometryBiochemistryAntibodyTumor necrosis factor alphaEnzymeBiotechnologyInternal medicineImmunologyBiologyIntellectual propertyComputer scienceOperating systemPaleontologyMedicineMonoclonal and Polyclonal Antibodies ResearchProtein purification and stabilityBiosimilars and Bioanalytical Methods