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Molecular modelling of mebendazole polymorphs as a potential colchicine binding site inhibitor

Ahmed A. Al‐Karmalawy, Muhammad Khattab

2020New Journal of Chemistry70 citationsDOI

Abstract

Form B of mebendazole is the form expected to bind more efficiently with the colchicine binding site within the tubulin protein.

Topics & Concepts

ChemistryMebendazoleColchicineBinding siteStereochemistryBiochemistryGeneticsZoologyBiologySynthesis and Biological EvaluationSynthesis and biological activityResearch on Leishmaniasis Studies
Molecular modelling of mebendazole polymorphs as a potential colchicine binding site inhibitor | Litcius