Brusatol ameliorates irinotecan-induced delayed diarrhea via inhibition of the cGAS-STING pathway and modulation of intestinal flora
Zixuan Lai, Yong Zhang, Weimu Huang, Di Wang, Chunting Liu, Mihong Ren, Xiaoqi Huang, Jiannan Chen, Jianhui Xie, Baoyi Chen, Zhengquan Lai, Youliang Xie
Topics & Concepts
IrinotecanDiarrheaStingPharmacologyFlora (microbiology)ChemistryMicrobiologyBiologyMedicineColorectal cancerInternal medicineBacteriaCancerAerospace engineeringGeneticsEngineeringinterferon and immune responsesIntraperitoneal and Appendiceal MalignanciesBacteriophages and microbial interactions