Solvent-free and montmorillonite K10-catalyzed domino reactions for the synthesis of pyrazoles with alkynylester as a dual synthon
Sesuraj Babiola Annes, Rajendhiran Saritha, Saravanan Subramanian, Bhaskaran Shankar, Subburethinam Ramesh
Abstract
A highly regioselective, solvent-free and montmorillonite K10 clay-catalyzed domino process with an unprecedented C–C bond formation reaction is described for the synthesis of new class of tri-substituted and di-substituted pyrazole derivatives.
Topics & Concepts
SynthonMontmorilloniteCatalysisRegioselectivityChemistryPyrazoleDominoCascade reactionSolventDual roleOrganic chemistryCombinatorial chemistryMedicinal chemistryMulticomponent Synthesis of HeterocyclesSynthesis and biological activityClick Chemistry and Applications