Necrostatin-1 attenuates Caspase-1-dependent pyroptosis induced by the RIPK1/ZBP1 pathway in ventilator-induced lung injury
Rongge Shao, Qiuwen Xie, Linghui Pan, Fei Lin, Ke Qin, Shaopeng Ming, Jinju Li, Xueke Du
Topics & Concepts
PyroptosisARDSBronchoalveolar lavageMedicineLungProinflammatory cytokineMechanical ventilationNecroptosisInflammationCaspase 1Western blotPharmacologyImmunologyProgrammed cell deathAnesthesiaChemistryApoptosisInternal medicineInflammasomeBiochemistryGeneInflammasome and immune disordersRespiratory Support and MechanismsImmune Response and Inflammation