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High Intensity Focused Ultrasound for Treatment of Bone Malignancies—20 Years of History

Sin Yuin Yeo, Grischa Bratke, Holger Grüll

2022Cancers20 citationsDOIOpen Access PDF

Abstract

High Intensity Focused Ultrasound (HIFU) is the only non-invasive method for percutaneous thermal ablation of tissue, with treatments typically performed either under magnetic resonance imaging or ultrasound guidance. Since this method allows efficient heating of bony structures, it has found not only early use in treatment of bone pain, but also in local treatment of malignant bone tumors. This review of 20 years of published studies shows that HIFU is a very efficient method for rapid pain relief, can provide local tumor control and has a very patient-friendly safety profile.

Topics & Concepts

High-intensity focused ultrasoundMedicineUltrasoundRadiologyAblationMagnetic resonance imagingTumor ablationThermal ablationPain reliefPercutaneousFocused ultrasoundLow-intensity pulsed ultrasoundSurgeryTherapeutic ultrasoundInternal medicineManagement of metastatic bone diseaseBone and Joint DiseasesBone fractures and treatments