Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABAA currents, but are not neurotoxic to the developing rat brain
Vesna Tešić, Srdjan M. Joksimovic, Nidia Quillinan, Kathiresan Krishnan, Douglas F. Covey, Slobodan M. Todorovic, Vesna Jevtović‐Todorović
Topics & Concepts
GABAA receptorNeuroactive steroidNeurotoxicityGABAergicPostsynaptic potentialLong-term potentiationInhibitory postsynaptic potentialPharmacologyNeuroscienceSubiculumChemistryTiagabinePropofolSynaptogenesisMedicineAnticonvulsantReceptorInternal medicineBiologyHippocampusEpilepsyBiochemistryDentate gyrusToxicityNeuroscience and Neuropharmacology ResearchAnesthesia and Neurotoxicity ResearchMemory and Neural Mechanisms