Litcius/Paper detail

T cells with split CARs specific for NKG2D ligands and PD-L1 exhibit improved selectivity towards monocyte-derived cells while effective in eliminating acute myeloid leukaemia in vivo

Lu Sun, Guangyi Jiang, Yu Yang Ng, Lin Xiao, Zhicheng Du, Shu Wang, Jianqing Zhu

2023Journal of Cancer Research and Clinical Oncology10 citationsDOIOpen Access PDF

Topics & Concepts

NKG2DMyeloidMonocyteCell biologyCancer researchChemistryT cellChimeric antigen receptorMolecular biologyBiologyImmunologyCytotoxic T cellImmune systemIn vitroBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses
T cells with split CARs specific for NKG2D ligands and PD-L1 exhibit improved selectivity towards monocyte-derived cells while effective in eliminating acute myeloid leukaemia in vivo | Litcius