Quantitative CT in mortality prediction in pulmonary fibrosis with or without emphysema.
Fatma Demirci Üçsular, Gülistan Karadeniz, Gülru Polat, Enver Yalnız, Aysu Ayrancı, Akın Çinkooğlu, Recep Savaş, Hatice Solmaz, Filiz Güldaval, Melih Büyükşirin
Abstract
AIM: We aimed to evaluate the quantitative CT analysis of patients with CPFE in comparison with IPF and emphysema. METHODS: Patients with CPFE(n:36), IPF(n:38) and emphysema(n:32) were retrospectively included in the study with the approval of the ethics committee. RESULTS: There was a positive correlation between total lung volume and FVC%, TLCO% and 6 MWT, and negative correlation between mMRC and mortality. Negative correlation was found between right, left lung density and FVC%, TLCO% and 6 MWT, and positive correlation between mortality. Also, total lung volume, right and left lung densities were significant in predicting mortality and cut-off values are ≤3831,> -778 and> -775, respectively (p = 0.040, 0.020, 0.013). CONCLUSION: Quantitative CT are guiding in predicting mortality of the disease.