CRISPR/Cas: History and Perspectives
Anna Shmakova, O. P. Shmakova, Anna Karpukhina, Yegor Vassetzky
Abstract
Abstract Discovery of the CRISPR/Cas system revolutionized biology and biomedicine in the 21st century. Here we discuss the milestones in the development of CRISPR/Cas genome editing technology, from the history of discovery to current developments, including medical applications. Technical and ethical problems associated with the use of CRISPR/Cas for editing human embryonic genomes are also discussed.
Topics & Concepts
CRISPRBiomedicineGenome editingComputational biologyGenomeBiologyComputer scienceGeneticsGeneCRISPR and Genetic EngineeringInnovation and Socioeconomic DevelopmentPluripotent Stem Cells Research