Collagen IV: a critical new starting point for engineering upper airways
Martina M. De Santis, Darcy E. Wagner
Abstract
<b>Collagen IV and integrin alpha 2 engagement is critical for forming differentiated airway epithelium capable of mucociliary clearance <i>in vitro</i>, but pre-vascularised scaffolds transplanted under immunosuppresion fail to maintain differentiated epithelium</b>https://bit.ly/2wT9XK5
Topics & Concepts
IntegrinEpitheliumAirwayCell biologyRespiratory epitheliumTissue engineeringIn vitroChemistryBiologyMedicinePathologyInternal medicineBiomedical engineeringReceptorSurgeryBiochemistryTracheal and airway disordersTissue Engineering and Regenerative MedicineEsophageal and GI Pathology