Expression of NOTCH1, NOTCH4, HLA-DMA and HLA-DRA is synergistically associated with T cell exclusion, immune checkpoint blockade efficacy and recurrence risk in ER-negative breast cancer
Dingxie Liu, Paul Hofman
Topics & Concepts
Immune checkpointTranscriptomeEstrogen receptorImmune systemCancer researchBreast cancerCarcinogenesisCancerGene signatureBiologyTriple-negative breast cancerImmunologyOncologyMedicineInternal medicineGeneGene expressionImmunotherapyGeneticsFerroptosis and cancer prognosisEpigenetics and DNA MethylationCerebrovascular and genetic disorders