Screening drug-induced liver injury through two independent parameters of lipid droplets and peroxynitrite with a π-extended coumarin-based NIR fluorescent probe
Bo Zhao, Shuo Zheng, Qingqing Liu, Chao Dong, Baoli Dong, Chunhua Fan, Zhengliang Lü, Juyoung Yoon, Juyoung Yoon
Topics & Concepts
FluorophorePeroxynitriteChemistryFluorescenceFalse positive paradoxBiophysicsLiver injuryBiochemistryPharmacologyMedicineEnzymeBiologyMachine learningPhysicsSuperoxideQuantum mechanicsComputer scienceDrug-Induced Hepatotoxicity and ProtectionAlcohol Consumption and Health EffectsLipid metabolism and biosynthesis