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Copy number amplification and SP1-activated lncRNA MELTF-AS1 regulates tumorigenesis by driving phase separation of YBX1 to activate ANXA8 in non-small cell lung cancer

Xiyi Lu, Jing Wang, Wei Wang, Chenfei Lu, Tianyu Qu, Xuezhi He, Xinyin Liu, Renhua Guo, Erbao Zhang

2022Oncogene66 citationsDOI

Topics & Concepts

CarcinogenesisBiologyCancer researchGene knockdownTranscription factorLong non-coding RNACell cycleRNACellGeneGeneticsCancer-related molecular mechanisms researchRNA Research and SplicingRNA modifications and cancer
Copy number amplification and SP1-activated lncRNA MELTF-AS1 regulates tumorigenesis by driving phase separation of YBX1 to activate ANXA8 in non-small cell lung cancer | Litcius