Detoxification of Aflatoxin B<sub>1</sub> by Phytochemicals in Agriculture and Food Science
Dian Yang, Sihua Zhang, Hongda Cao, Huan Wu, Liang Yang, Chun‐Bo Teng, Hai‐Fan Yu
Abstract
Aflatoxin B 1 (AFB 1 ), the most toxic and harmful mycotoxin, has a high likelihood of occurring in animal feed and human food, which seriously affects agriculture and food safety and endangers animal and human health. Recently, natural plant products have attracted widespread attention due to their low toxicity, high biocompatibility, and simple composition, indicating significant potential for resisting AFB 1 . The mechanisms by which these phytochemicals resist toxins mainly involve antioxidative, anti-inflammatory, and antiapoptotic pathways. Moreover, these substances also inhibit the genotoxicity of AFB 1 by directly influencing its metabolism in vivo, which contributes to its elimination. Here, we review various phytochemicals that resist AFB 1 and their anti-AFB 1 mechanisms in different animals, as well as the common characteristics of phytochemicals with anti-AFB 1 function. Additionally, the shortcomings of current research and future research directions will be discussed. Overall, this comprehensive summary contributes to the better application of phytochemicals in agriculture and food safety.