Identification of 5-[5-cyano-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamido] thiazole-4-carboxylic acid as a promising dual inhibitor of urate transporter 1 and xanthine oxidase
Fengwei Lin, Ming Sun, Jun Gao, Bing Zhang, Qing Mao, Ziyang Bao, Chao Shen, Qiuhua Li, Han Wang, Shaojie Wang
Topics & Concepts
ChemistryTranilastXanthine oxidaseThiazoleHyperuricemiaIndole testStereochemistryAllopurinolUric acidIn vivoPharmacologyBiochemistryEnzymeBiotechnologyBiologyMedicinePathologyGout, Hyperuricemia, Uric AcidCase Reports on HematomasAlcohol Consumption and Health Effects