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Synthesis of <i>N</i>-alkoxy amines and hydroxylamines <i>via</i> the iridium-catalyzed transfer hydrogenation of oximes

Yanping Xia, Sen Wang, Rui Miao, Jianhua Liao, Lu Ouyang, Renshi Luo

2022Organic & Biomolecular Chemistry16 citationsDOI

Abstract

An efficient and practical strategy for the construction of N -alkoxy amines and hydroxylamines through the corresponding oximes is described via an Ir-catalyzed acid-assisted system with high yields and a good substrate scope.

Topics & Concepts

ChemistryIridiumAlkoxy groupCatalysisSubstrate (aquarium)Transfer hydrogenationCombinatorial chemistryScope (computer science)Organic chemistryMedicinal chemistryRutheniumGeologyAlkylOceanographyProgramming languageComputer scienceAsymmetric Hydrogenation and CatalysisChemical Synthesis and AnalysisNanomaterials for catalytic reactions
Synthesis of <i>N</i>-alkoxy amines and hydroxylamines <i>via</i> the iridium-catalyzed transfer hydrogenation of oximes | Litcius