Impact of Daridorexant, a Dual Orexin Receptor Antagonist, on Cardiac Repolarization Following Bedtime Dosing: Results from a Thorough QT Study Using Concentration-QT Analysis
Uta Schilling, Andrea Henrich, Clemens Muehlan, Andreas Krause, Jasper Dingemanse, Mike Ufer
Topics & Concepts
MedicineMoxifloxacinQT intervalPlaceboAssay sensitivityCrossover studyPharmacokineticsBedtimeDosingConfidence intervalPharmacologyHypokalemiaAnesthesiaInternal medicineAntibioticsBiologyAlternative medicinePathologyMicrobiologySleep and Wakefulness ResearchSleep and Work-Related FatigueEEG and Brain-Computer Interfaces