Intragastric and atomized administration of canagliflozin inhibit inflammatory cytokine storm in lipopolysaccharide-treated sepsis in mice: A potential COVID-19 treatment
Yaoyun Niu, Yang Chen, Pengbo Sun, Yangyang Wang, Jingyi Luo, Yipei Ding, Weidong Xie
Topics & Concepts
Cytokine stormCytokineSepsisLipopolysaccharideMedicinePharmacologyLungHypoxia (environmental)In vivoInflammationImmunologyInternal medicineBiologyChemistryDiseaseInfectious disease (medical specialty)Coronavirus disease 2019 (COVID-19)OxygenBiotechnologyOrganic chemistryCOVID-19 Clinical Research StudiesPancreatitis Pathology and TreatmentCalcium signaling and nucleotide metabolism