<i>Para</i>‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
Michael Berger, Marola S. Lenhard, Siegfried R. Waldvogel
Abstract
Abstract The para ‐selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF 2 is reported, with Et 3 N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set‐up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %.
Topics & Concepts
Hypervalent moleculeElectrochemistryFluorideChemistryElectrolyteCombinatorial chemistryOrganic chemistryInorganic chemistryPhysical chemistryElectrodeReagentFluorine in Organic ChemistryRadical Photochemical ReactionsOxidative Organic Chemistry Reactions