Synthesis and antioxidant properties of some new 5-phenethyl-3-thio-1,2,4-triazoles
T. V. Ihnatova, А. Г. Каплаушенко, Yuliia Frolova, Evheniy Pryhlo
Abstract
Novel derivatives of 4-R-5-phenethyl-4H-1,2,4-triazole-3-thiols were synthesized. The proposed approaches and developed synthetic protocols provided the possibility to design 4-R-5-phenethyl-4H-1,2,4-triazole-3-thiols and their derivatives have been shown. The antioxidant activity of the synthesized compounds was evaluated in vitro by the method of the non-enzymatic initiation of BOD with salts of iron (II). When compared with existing antioxidants, some of our compounds were found to be more potent.
Topics & Concepts
Thio-AntioxidantChemistryTriazoleCombinatorial chemistryIn vitroEnzymeOrganic chemistryBiochemistryScientific Research and StudiesDiverse Scientific Research in UkraineUkrainian Cultural and Linguistic Studies