Litcius/Paper detail

MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction

Zhangcheng Ding, Rui Wang, Yuhua Li, Xiaodong Wang

2025Molecular Cell56 citationsDOI

Topics & Concepts

NecroptosisBiologyCell biologyStingMitochondrial DNAMitochondrionVirologyProgrammed cell deathApoptosisGeneticsGeneAerospace engineeringEngineeringinterferon and immune responsesViral Infections and VectorsInflammasome and immune disorders