STMN2 mediates nuclear translocation of Smad2/3 and enhances TGFβ signaling by destabilizing microtubules to promote epithelial-mesenchymal transition in hepatocellular carcinoma
Fang-Jing Zhong, Bo Sun, Momo Cao, Cong Xu, Yiming Li, Lian‐Yue Yang
Topics & Concepts
Epithelial–mesenchymal transitionCancer researchMetastasisBiologySMADGene knockdownSignal transductionVimentinHepatocellular carcinomaHCCSCancerCell biologyImmunologyCell cultureImmunohistochemistryGeneticsCancer Cells and MetastasisTGF-β signaling in diseasesGenetic factors in colorectal cancer