Telacebec (Q203), a New Antituberculosis Agent
Veronique de Jager, Rodney Dawson, Christo van Niekerk, Jane Hutchings, Jeongjun Kim, Naadira Vanker, Lize van der Merwe, Jin‐Ho Choi, Kiyean Nam, Andreas H. Diacon
Abstract
confirmed the results.In addition, the isolation of SARS-CoV-2 from both samples in cell culture of Caco-2 cells indicated potential infectivity (see the Supplementary Appendix, available with the full text of this letter at NEJM.org).These two persons were subsequently isolated from the cohort and transferred to the Infectious Disease Unit at University Hospital Frankfurt for further evaluation and observation on the following day.After a thorough evaluation in the hospital ward, a faint rash and minimal pharyngitis were observed in one patient.Both patients remained well and afebrile 7 days after admission.In this effort to evacuate 126 people from Wuhan to Frankfurt, a symptom-based screening process was ineffective in detecting SARS-CoV-2 infection in 2 persons who later were found to have evidence of SARS-CoV-2 in a throat swab.We discovered that shedding of potentially infectious virus may occur in persons who have no fever and no signs or only minor signs of infection.