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Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity

J. Alberto Ortega, Elizabeth L. Daley, Sukhleen Kour, Marisa Samani, Liana Tellez, Haley S. Smith, Elizabeth Hall, Y. Taylan Esengul, Yung‐Hsu Tsai, Tania F. Gendron, Christopher J. Donnelly, Teepu Siddique, Jeffrey N. Savas, Udai Bhan Pandey, Evangelos Kiskinis

2020Neuron88 citationsDOIOpen Access PDF

Topics & Concepts

C9orf72Trinucleotide repeat expansionNeurodegenerationBiologyCell biologyTranslation (biology)ProteomeFrontotemporal dementiaGeneticsMessenger RNAGeneMedicineDementiaAllelePathologyDiseaseAmyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative DiseasesMitochondrial Function and Pathology
Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity | Litcius