Collagen/GAG scaffolds activated by RALA-siMMP-9 complexes with potential for improved diabetic foot ulcer healing
Leping Yan, Irene Mencía Castaño, Rukmani Sridharan, Domhnall Kelly, Mark Lemoine, Brenton Cavanagh, Nicholas Dunne, Helen O. McCarthy, Fergal J. O’Brien
Topics & Concepts
Diabetic footWound healingDownregulation and upregulationDiabetic foot ulcerMatrix metalloproteinaseCell cultureRegeneration (biology)ChemistryIn vitroGene expressionCell biologyMolecular biologyMedicineDiabetes mellitusGeneBiochemistryBiologyImmunologyEndocrinologyGeneticsWound Healing and TreatmentsProtease and Inhibitor MechanismsAntimicrobial Peptides and Activities