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Association Between Cancer-Related Fatigue and Falls in Patients With Myeloproliferative Neoplasms: Results of a Multicenter Cross-Sectional Survey From the East German Study Group for Hematology and Oncology (OSHO #97)

Sabine Felser, Martin Gube, Julia Gruen, Philipp Ie Coutre, Susann Schulze, Lars‐Olof Muegge, Christian Junghanß, Sabina Ulbricht

2022Integrative Cancer Therapies10 citationsDOIOpen Access PDF

Abstract

OBJECTIVE: This study retrospectively examined the association between cancer-related fatigue (CrF) and the number of falls during the last 12 months in patients with myeloproliferative neoplasms (MPNs). METHODS: A multicenter, 1-time anonymous survey was conducted using analog and digital questionnaires. Sex-stratified multinomial logistic regression analysis was applied to investigate the association between CrF and number of falls. All analyses were adjusted for age, school education, body mass index, MPN subtype, and quality of life. RESULTS: = .153). There were no differences between women and men in terms of CrF between individuals with more than 1 fall, whereas women with 1 fall had a higher CrF compared to those without a fall (RRR = 1.019; 95% CI [1.002-1.039]), respectively. CONCLUSION: CrF increases the risk of falls in women with MPN. Physicians should evaluate and manage CrF symptoms and implement fall prevention strategies for those who are at increased risk. Further research is needed to better understand the effects of CrF on gait performance and associated fall risk.

Topics & Concepts

MedicineInternal medicineLogistic regressionCross-sectional studyBody mass indexCancerHematologyPhysical therapyPathologyMyeloproliferative Neoplasms: Diagnosis and TreatmentAcute Myeloid Leukemia ResearchChronic Myeloid Leukemia Treatments