NRF2 is essential for iron-overload stimulated osteoclast differentiation through regulation of redox and iron homeostasis
Jian Zhang, Lingyan Zhang, Gang Yao, Hai Zhao, Shuguang Wu
Topics & Concepts
OsteoclastOxidative stressCell biologyFerroportinChemistryDownregulation and upregulationReactive oxygen speciesFerritinBone resorptionEndocrinologyBiologyBiochemistryMetabolismReceptorGeneIron homeostasisTrace Elements in HealthFerroptosis and cancer prognosisDrug Transport and Resistance Mechanisms