Recent advances in spheroid-based microfluidic models to mimic the tumour microenvironment
Jooyoung Ro, Junyoung Kim, Yoon‐Kyoung Cho
Abstract
microenvironment. This review provides an overview of the advantages of 3D spheroid cultures with a summary of the recent applications for tumour microenvironment-focused cellular interactions, as well as the studies on spheroids and external stimuli. These 3D tumour spheroid-based microfluidic devices will provide a platform for a better understanding of cellular and external interactions, as well as the discovery of cancer therapeutics.
Topics & Concepts
SpheroidMicrofluidicsTumor microenvironmentCell biologyChemistryBiologyNanotechnologyCell cultureTumor cellsMaterials scienceCancer researchGenetics3D Printing in Biomedical ResearchInnovative Microfluidic and Catalytic Techniques InnovationCancer Cells and Metastasis