Machine learning-guided engineering of genetically encoded fluorescent calcium indicators
Sarah J. Wait, Marc Expòsit, Sophia Lin, Michael Rappleye, Justin Daho Lee, Samuel A. Colby, Lily Torp, Anthony Asencio, Annette C. Smith, Michael Regnier, Farid Moussavi‐Harami, David Baker, Christina K. Kim, A. Berndt
Topics & Concepts
In silicoMutagenesisComputer scienceFluorescent proteinMachine learningProtein engineeringArtificial intelligenceEnsemble learningComputational biologyMutationBiologyGeneticsBiochemistryGreen fluorescent proteinGeneEnzymeCRISPR and Genetic EngineeringAdvanced Fluorescence Microscopy TechniquesReceptor Mechanisms and Signaling