A highly sensitive silicon nanowire array sensor for joint detection of tumor markers CEA and AFP
Ke Lu, Chaoran Liu, Gaofeng Wang, Weihuang Yang, Kai Fan, S. K. Lazarouk, В. А. Лабунов, Linxi Dong, Dujuan Li, Xun Yang
Abstract
of CEA in 0.1× PBS were 0.99885 and 0.99677, respectively. Furthermore, the sensor could distinguish CEA/AFP from interferents at high concentrations. Importantly, even in serum samples, our sensor could successfully detect CEA/AFP. This demonstrates the promising clinical development of our sensor.
Topics & Concepts
Carcinoembryonic antigenSilicon nanowiresDetection limitMaterials scienceLiver cancerWaferNanowireBiomedical engineeringNanotechnologyCancerMedicineChemistryChromatographyInternal medicineNanowire Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniquesAnalytical Chemistry and Sensors